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Marzena Pazgier Selected Research

Tumor Suppressor Protein p53

9/2021Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for P53 activation and tumor suppression.
2/2019Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
8/2010D-peptide inhibitors of the p53-MDM2 interaction for targeted molecular therapy of malignant neoplasms.
4/2010Systematic mutational analysis of peptide inhibition of the p53-MDM2/MDMX interactions.

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Marzena Pazgier Research Topics

Disease

20Infections
02/2022 - 01/2007
7Neoplasms (Cancer)
09/2021 - 09/2008
5COVID-19
07/2022 - 01/2021
3HIV Infections (HIV Infection)
01/2020 - 01/2016
3Viremia
12/2019 - 09/2015
1Disease Progression
01/2020
1Virus Diseases (Viral Diseases)
12/2019
1Sexually Transmitted Diseases (Sexually Transmitted Disease)
12/2019
1Reinfection
11/2019
1Bacillary Dysentery (Shigellosis)
01/2018
1Acquired Immunodeficiency Syndrome (AIDS)
01/2017
1Sepsis (Septicemia)
01/2013
1Glioblastoma (Glioblastoma Multiforme)
08/2010
1Crohn Disease (Crohn's Disease)
08/2009
1Inflammation (Inflammations)
01/2007

Drug/Important Bio-Agent (IBA)

15AntibodiesIBA
10/2021 - 01/2013
9VaccinesIBA
04/2021 - 09/2015
7EpitopesIBA
10/2021 - 01/2016
6Neutralizing AntibodiesIBA
01/2022 - 01/2017
4Glycoproteins (Glycoprotein)IBA
07/2022 - 01/2016
4Peptides (Polypeptides)IBA
09/2021 - 08/2010
4Tumor Suppressor Protein p53IBA
09/2021 - 04/2010
4DefensinsIBA
01/2018 - 01/2007
3Proteins (Proteins, Gene)FDA Link
07/2007 - 01/2007
2Pharmaceutical PreparationsIBA
07/2022 - 04/2010
21- (3- (2- hydroxyl- 3- piperidin- 1- yl- propoxy)- phenoxy)- 3- piperidin- 1- ylpropan- 2- olIBA
07/2022 - 02/2022
2Antiviral Agents (Antivirals)IBA
01/2019 - 02/2016
2Oncogene Proteins (Oncogene Protein)IBA
07/2012 - 08/2010
1AIDSVAXIBA
01/2020
1AntigensIBA
01/2020
1Virulence Factors (Pathogenicity Factors)IBA
01/2018
1Viral ProteinsIBA
01/2017
1Broadly Neutralizing AntibodiesIBA
01/2017
1Immunoglobulin G (IgG)IBA
02/2016
1Fc Receptors (Fc Receptor)IBA
09/2015
1human neutrophil peptide 1IBA
01/2013
1BAS00127538IBA
01/2013
1Muramic Acids (Muramic Acid)IBA
01/2013
1muramyl- NAc- (pentapeptide)pyrophosphoryl- undecaprenolIBA
01/2013
1Liposomes (Liposome)IBA
08/2010
1Antineoplastic Agents (Antineoplastics)IBA
08/2010
1IntegrinsIBA
08/2010
1cyclic arginine-glycine-aspartic acid peptideIBA
08/2010
1Histidine (L-Histidine)FDA Link
08/2009
1Arginine (L-Arginine)FDA Link
08/2009
1SurvivinIBA
09/2008
1alpha-DefensinsIBA
08/2008
1Amino AcidsFDA Link
01/2007

Therapy/Procedure

6Therapeutics
07/2022 - 03/2009
2Immunotherapy
07/2022 - 02/2022
1Molecular Targeted Therapy
08/2010